Bio Info SIG: Systems Biology & Predictive Biosimulation in Pharmaceutical R&D



  • The Monthly Meeting of the Bio Informatics SIG



    Alex L. Bangs – Co-Founder & Chief Technology Officer, Entelos

    Presentation Overview

    Systems Biology uses an integrative approach to study complex biological systems with the hope of understanding both human health and disease. Large-scale simulation models of human physiology -- at the disease, cell, and pathway level -- are already being used to discover and develop the targets, compounds, and biomarkers most meaningful to the onset, progression, and treatment of complex diseases. Virtual patients, each a unique representation of genetic, physiological, lifestyle and environmental conditions, allow the unprecedented ability to rapidly generate and test hypotheses related to target and compound efficacy and mechanisms of action. The impact systems biology is having in pharmaceutical R&D today will be discussed with case studies.


    About the Presenter

    Alex L. Bangs

    Mr. Bangs manages Entelos’ technology groups, including software development, quality assurance, and information technology. He has over 15 years of experience in the development and integration of end-user, database, analytical, and embedded systems applications. Mr. Bangs has held technical and management positions at Strategic Decisions Group (SDG), Oak Ridge National Laboratory, Honeybee Robotics, and the Institute for Defense Analyses. He has significant expertise in the integration of complex systems, which he first applied to robotics and medical instrumentation then later to the development of decision analysis systems such as PowerCoach™, Whiteboard™, and the Entelos PhysioLab platform. He holds an A.B. in computer science and engineering sciences from Harvard College and an M.S. in computer science from the University of Tennessee.


    Event Logistics:



    Hanson Bridgett

    333 Market Street, 21st Floor

    San Francisco, CA, 94105

    Note: Location provided courtesy of Hanson, Bridgett, Marcus, Vlahos, Rudy, LLP.


    6:30 - 7:00 p.m. Registration and Networking

    7:00 - 9:00 p.m. Presentation



    $15 at the door for non-SDForum members

    No charge for SDForum members

    Please call 408.494.8378 for student memberships

    Registration NOT required