Bio Info SIG (SF): Genome and Proteome Information Integration
New Opportunities in Biotechnology. The integration of proteomic and genomic information provides a framework for new innovation and the convergence of biotechnology and computer science is open ground for those who can straddle both arenas.
The complete genome sequence for more than 100 different organisms in the simple form of 4 letters, A, C, G, and T, has created exciting new opportunities in information management and interpretation. The translation of identified genes into 20 letters of the amino acid code has provided the initial proteomics information. Subsequent information includes protein sequence information, 3D protein structure, cell location and function, etc. The integration of proteomic and genomic information provides a framework for new innovation and the convergence of biotechnology and computer science is open ground for those who can straddle both arenas. Systems biology, personalized medicine, and biochip diagnostics are just a few of the emerging fields.
About the Presenter
Dr. Mize recently joined DNA BRIDGES a firm known internationally for expert consulting and professional services in biotechnology, pharmaceutical and diagnostic industries. In addition, she serves on the Scientific Advisory Board for the life sciences division of the Women’s Technology Cluster an incubator for startup information technology and biotechnology businesses.
Dr. Mize has more than 15 years experience in Biotechnology, with extensive experience in novel genomics and proteomics software applications, innovative technology implementation for industry and academia, and expertise in proteomics, genomics, and bioinformatics, 3D protein structure, small drug modeling (QSAR for toxicity), microarray GeneChip analysis, and Mass Spectroscopy. As a consultant, Dr. Mize has reviewed and appraised technologies for several startup Biotechnology companies, composed business plans and V.C. presentations. As Director of Protein Bioinformatics at Hyseq, a Genomics company, she created and supervised three groups: Computational Biology, Intellectual Property Informatics, and Data Integration. Previously, Dr. Mize was research scientist at Ciphergen Biosystems, a Proteomics company, and staff scientist at Alza Corp. She received her B.S. from the University of California, Berkeley, and her Ph.D. from the University of California, San Francisco. Subsequently, she completed postdoctoral studies in the Cell Biology Programme at the European Molecular Biology Laboratory (EMBL, GenBank), Heidelberg, Germany, and at Genentech in the Department of Molecular Biology. In the course of her work at Ciphergen and Hyseq, Dr. Mize holds more than 25 U.S. and European patent applications.
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